Handling checkbox inputs in React requires proper controlled component patterns to manage checked state, handle user interactions, and maintain form data consistency. As the creator of CoreUI, a widely used open-source UI library, I’ve implemented checkbox handling in countless React form components for user preferences, multi-selection interfaces, permission management, and complex form validation across enterprise applications. From my expertise, the most effective approach is to use controlled components with checked property and onChange handlers. This method provides predictable state management, form validation integration, and proper user experience while maintaining React’s unidirectional data flow principles.