Using useMemo is essential for optimizing React applications by memoizing expensive calculations and preventing unnecessary re-computations during renders. As the creator of CoreUI, a widely used open-source UI library, I’ve implemented useMemo in numerous React components for data processing, filtering operations, and complex calculations in performance-critical enterprise applications. From my expertise, the most effective approach is to use useMemo for expensive computations with proper dependency arrays. This method provides significant performance improvements while maintaining code readability and preventing optimization-related bugs through careful dependency management.